Albumin Nuclease-Free

<strong>Albumin Nuclease-Free</strong>_x000D_ <strong>Catalog number:</strong> B2018223_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 66.4 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Albumin Nuclease-Free_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chandler RJ, Venturoni LE, Liao J, Hubbard BT, Schneller JL, Hoffmann V, Gordo S, Zang S, Ko CW, Chau N, Chiang K, Kay MA, Barzel A, Venditti CP. Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia Hepatology. 2021 Jun;73(6):2223-2237._x000D_ 2: Padula A, Spinelli M, Nusco E, Bujanda Cundin X, Capolongo F, Campione S, Perna C, Bastille A, Ericson M, Wang CC, Zhang S, Amoresano A, Nacht M, Piccolo P. Genome editing without nucleases confers proliferative advantage to edited hepatocytes and corrects Wilson disease JCI Insight. 2023 Nov 8;8(21):e171281._x000D_ 3: Venturoni LE, Chandler RJ, Liao J, Hoffmann V, Ramesh N, Gordo S, Chau N, Venditti CP. Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing Mol Genet Metab. 2022 Sep-Oct;137(1-2):1-8._x000D_ 4: Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency Mol Ther. 2017 Nov 1;25(11):2477-2489._x000D_ 5: Ponomareva RB, Zelepuga EA, Medvedev ML. [Nuclease conjugates with ligand-free serum albumin] Nauchnye Doki Vyss Shkoly Biol Nauki. 1992;(2):86-9._x000D_ 6: McKeown BJ. An acetylated (nuclease-free) bovine serum albumin in a PCR buffer inhibits amplification Biotechniques. 1994 Aug;17(2):246-8._x000D_ 7: Zhang S, Bastille A, Gordo S, Ramesh N, Vora J, McCarthy E, Zhang X, Frank D, Ko CW, Wu C, Walsh N, Amarwani S, Liao J, Xiong Q, Drouin L, Hebben M, Chiang K, Chau BN. Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia PLoS One. 2022 Sep 20;17(9):e0274774._x000D_ 8: Konwar B, Mullick P, Das G, Ramesh A. Anthraquinone-Based Ligands as MNase Inhibitors: Insights from Inhibition Studies and Generation of a Payload Nanocarrier for Potential Anti-MRSA Therapy ChemMedChem. 2023 Jul 3;18(13):e202200711._x000D_ 9: Elkhashab M, Dilek Y, Foss M, Creemers LB, Howard KA. A Modular Albumin-Oligonucleotide Biomolecular Assembly for Delivery of Antisense Therapeutics Mol Pharm. 2024 Feb 5;21(2):491-500._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8373169">10: Pastori RL, Schoenberg DR. The nuclease that selectively degrades albumin mRNA in vitro associates with Xenopus liver polysomes through the 80S ribosome complex Arch Biochem Biophys. 1993 Sep;305(2):313-9. </a>_x000D_ _x000D_ <strong>Products Related to Albumin Nuclease-Free can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>