N-Acetyl-DL-phenylalanine β-naphthyl ester

N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin[1].

Product Specifications

CAS Number

[20874-31-1]

UNSPSC

12171500

Hazard Statement

H302

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/n-acetyl-dl-phenylalanine-β-naphthyl-ester.html

Solubility

10 mM in DMSO

Smiles

CC(NC(C(OC1=CC2=CC=CC=C2C=C1)=O)CC3=CC=CC=C3)=O

Molecular Formula

C21H19NO3

Molecular Weight

333.38

Precautions

P264-P270-P330-P501

References & Citations

[1]Kar NC, et al. Acetyl-DL-phenylalanine beta-naphthyl esterase activity in human muscle disease. Biochem Med. 1978 Aug. 20 (1) :63-9. |[2]Yakoby N, et al. A simple method to determine trypsin and chymotrypsin inhibitory activity. J Biochem Biophys Methods. 2004 Jun 30. 59 (3) :241-51. |[3]Kourteva I, et al. Assay for enzyme inhibition: detection of natural inhibitors of trypsin and chymotrypsin. Anal Biochem. 1987 May 1. 162 (2) :345-9. |[4]Darani HY, et al. An association between Schistosoma mansoni worms and an enzymatically-active protease/peptidase in mouse blood. Parasitology. 2008 Apr. 135 (4) :467-72. |[5]P Tsung, et al. Isolation of an N-acetyl-DL-phenylalanine beta-naphthyl esterase from rabbit peritoneal polymorphonuclear leukocytes. Biochim Biophys Acta. 1975 Sep 22;403 (1) :98-105.