PPARγ agonist 11
PPARγ agonist 11 (compound 20) is a selective agonist of PPARγ (EC50: 0.1 μM) [1].
Product Specifications
CAS Number
1143573-33-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pparγ-agonist-11.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
CC(C(O)=O)(OC1=CC=CC2=C1CCCN2CCCOC3=CC=C(C=C3CCC)C(C4=CC=C(C=C4)C5=CC=CC=C5)=O)C
Molecular Formula
C38H41NO5
Molecular Weight
591.74
Precautions
H302, H315, H319, H335
References & Citations
[1]Lin CH, et al. Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists. J Med Chem. 2009 Apr 23;52 (8) :2618-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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