Anti-ITGB3 (Tadocizumab)-SPDB-DM4 ADC
This ADC product is comprised of an anti-ITGB3 Fab' fragment conjugated via a SPDB linker to DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6361612-01 0.2 mL
UPF2, ID (UPF2, KIAA1408, RENT2, Regulator of nonsense transcripts 2, Nonsense mRNA reducing factor 2, Up-frameshift suppressor 2 homolog) (Azide free) (HRP)
Ask
View Details MBS6361612-02 5x 0.2 mL
UPF2, ID (UPF2, KIAA1408, RENT2, Regulator of nonsense transcripts 2, Nonsense mRNA reducing factor 2, Up-frameshift suppressor 2 homolog) (Azide free) (HRP)
Ask
View Details MBS1426323-01 0.02 mg (E-Coli)
Recombinant Drosophila melanogaster Glutathione S-transferase D6 (GstD6)
Ask
View Details 
MBS1426323-02 0.1 mg (E-Coli)
Recombinant Drosophila melanogaster Glutathione S-transferase D6 (GstD6)
Ask
View Details 
MBS1426323-03 0.02 mg (Yeast)
Recombinant Drosophila melanogaster Glutathione S-transferase D6 (GstD6)
Ask
View Details