Anti-ITGB3 (Tadocizumab)-SPDB-DM4 ADC
This ADC product is comprised of an anti-ITGB3 Fab' fragment conjugated via a SPDB linker to DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
240348-01 100 mg
Na-Boc-Na, d, d-tris (3-Boc-aminopropyl) -L-ornithine 99+% (TLC)
Sign In for Pricing
View Details 240348-02 250 mg
Na-Boc-Na, d, d-tris (3-Boc-aminopropyl) -L-ornithine 99+% (TLC)
Sign In for Pricing
View Details 
240348-03 1 g
Na-Boc-Na, d, d-tris (3-Boc-aminopropyl) -L-ornithine 99+% (TLC)
Sign In for Pricing
View Details 240348-04 5 g
Na-Boc-Na, d, d-tris (3-Boc-aminopropyl) -L-ornithine 99+% (TLC)
Sign In for Pricing
View Details NBP2-33176AF594 0.1 mL
Mouse Monoclonal Cytokeratin 18 Antibody (DA7) [Alexa Fluor 594]
Sign In for Pricing
View Details 
058102-01 10 µg
PR Domain Containing Protein 16 (PRDM16), Recombinant, Human, His-Tag, TRxA-Tag
Sign In for Pricing
View Details