Anti-ITGA4+ITGB7 (Crenezumab)-SMCC-DM1 ADC
This ADC product is comprised of an anti-ITGA4+ITGB7 monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6136959-01 0.1 mL
HES5 (Transcription Factor HES-5, Class B Basic Helix-loop-helix Protein 38, bHLHb38, Hairy and Enhancer of Split 5, BHLHB38) APC
Ask
View Details MBS6136959-02 5x 0.1 mL
HES5 (Transcription Factor HES-5, Class B Basic Helix-loop-helix Protein 38, bHLHb38, Hairy and Enhancer of Split 5, BHLHB38) APC
Ask
View Details MPX1216K Each
Magic™ Membrane Protein Human FAM74A3 (Family with sequence similarity 74 member A3) Expressed in vitro E.coli expression system, Full Length
Ask
View Details