Anti-CD3E (Otelixizumab)-SMCC-DM1 ADC
This ADC product is comprised of an anti-CD3E monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
302825-HRP 200 µL
Ubiquilin 4 (Ubiquilin-4, Ataxin-1 interacting Ubiquitin-like Protein, A1Up, Ataxin-1 Ubiquitin-like-interacting Protein A1U, Connexin43-interacting Protein of 75kD, CIP75, UBQLN4, C1orf6, CIP75, UBIN) (HRP) discontinued
Sign In for Pricing
View Details bs-9739R-BF405 100 µL
CNTD Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Sign In for Pricing
View Details