Anti-CSF1R (Emactuzumab)-MC-MMAF ADC
This ADC product is comprised of an anti-CSF1R monoclonal antibody conjugated via a MC linker to MMAF. The MMAF is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAF binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
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APPBP1 (59kD, Amyloid beta Precursor Protein Binding Protein 1 59kD, Amyloid beta Precursor Protein Binding Protein 1 59kD, Amyloid beta Precursor Protein Binding Protein 1, Amyloid beta Precursor Protein-binding Protein 1, Amyloid Protein Binding Protein 1, Amyloid Protein-binding Protein 1, APP BP1, APP-BP1, APPBP 1, HPP 1, HPP1, NAE 1, NAE1, NEDD8 Activating Enzyme E1 Regulatory Subunit, NEDD8 Activating Enzyme E1 Subunit 1, NEDD8 Activating Enzyme E1 Subunit, NEDD8-activating Enzyme E1 Regulatory Subunit, Proto Oncogene Protein 1, Proto-oncogene Protein 1, Protooncogene Protein 1, Ula 1, ULA1_HUMAN)
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