Anti-VEGFA (Vanucizumab)-SMCC-DM1 ADC
This ADC product is comprised of an anti-VEGFA bispecific antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-9980R-PerCP 100 µL
C21orf55 Polyclonal Antibody, PerCP Conjugated
Sign In for Pricing
View Details 
MBS6309142-01 0.1 mL
ID3, NT (ID3, 1R21, BHLHB25, HEIR1, DNA-binding protein inhibitor ID-3, Class B basic helix-loop-helix protein 25, Helix-loop-helix protein HEIR-1, ID-like protein inhibitor HLH 1R21, Inhibitor of DNA binding 3) (MaxLight 650)
Sign In for Pricing
View Details