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Anti-NOTCH2 (Tarextumab)-MC-Vc-PAB-SN38 ADC

This ADC product is comprised of an anti-NOTCH2 monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38. The SN-38 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage.

Product Specifications

CAS Number

9007-83-4

Format

Solution

Shipping Conditions

Ice Packs

Storage Conditions

-20°C

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