Anti-NOTCH2 (Tarextumab)-MC-Vc-PAB-SN38 ADC
This ADC product is comprised of an anti-NOTCH2 monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38. The SN-38 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
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