Human ATOX1 Protein

<strong>Human ATOX1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011807_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Metal transport protein., Copper transport protein protein, Antioxidant protein 1 protein, Copper transport protein ATOX1 ATX1 protein, ATOX-1, HAH1 protein, ATX1 protein, ATOX-1 protein, ATOX1, ATOX 1, ATOX 1 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen L, Li N, Zhang M, Sun M, Bian J, Yang B, Li Z, Wang J, Li F, Shi X, Wang Y, Yuan F, Zou P, Shan C, Wang J. APEX2-based Proximity Labeling of Atox1 Identifies CRIP2 as a Nuclear Copper-binding Protein that Regulates Autophagy Activation Angew Chem Int Ed Engl. 2021 Nov 22;60(48):25346-25355._x000D_ 2: Perkal O, Qasem Z, Turgeman M, Schwartz R, Gevorkyan-Airapetov L, Pavlin M, Magistrato A, Major DT, Ruthstein S. Cu(I) Controls Conformational States in Human Atox1 Metallochaperone: An EPR and Multiscale Simulation Study J Phys Chem B. 2020 Jun 4;124(22):4399-4411._x000D_ 3: Belviso BD, Galliani A, Lasorsa A, Mirabelli V, Caliandro R, Arnesano F, Natile G. Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization Inorg Chem. 2016 Jul 5;55(13):6563-73._x000D_ 4: Chen J, Jiang Y, Shi H, Peng Y, Fan X, Li C. The molecular mechanisms of copper metabolism and its roles in human diseases Pflugers Arch. 2020 Oct;472(10):1415-1429._x000D_ 5: Hatori Y, Lutsenko S. An expanding range of functions for the copper chaperone/antioxidant protein Atox1 Antioxid Redox Signal. 2013 Sep 20;19(9):945-57._x000D_ 6: Kahra D, Mondol T, Niemiec MS, Wittung-Stafshede P. Human Copper Chaperone Atox1 Translocates to the Nucleus but does not Bind DNA In Vitro Protein Pept Lett. 2015;22(6):532-8._x000D_ 7: Luchinat E, Secci E, Cencetti F, Bruni P. Sequential protein expression and selective labeling for in-cell NMR in human cells Biochim Biophys Acta. 2016 Mar;1860(3):527-33._x000D_ 8: Tian Y, Fang T, Yuan S, Zheng Y, Arnesano F, Natile G, Liu Y. Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1 Metallomics. 2018 May 23;10(5):745-750._x000D_ 9: Nardella MI, Rosato A, Belviso BD, Caliandro R, Natile G, Arnesano F. Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione Int J Mol Sci. 2019 Sep 6;20(18):4390._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25673218">10: Petzoldt S, Kahra D, Kovermann M, Dingeldein AP, Niemiec MS, Ådén J, Wittung-Stafshede P. Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro Biometals. 2015 Jun;28(3):577-85. </a>_x000D_ _x000D_ <strong>Products Related to Human ATOX1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>