Recombinant Canine Carbonic Anhydrase IX/CA9 Protein (hFc Tag)

<strong>Recombinant Canine Carbonic Anhydrase IX/CA9 Protein (hFc Tag)</strong>_x000D_ <strong>Catalog number:</strong> B2019136_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 67.6 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Recombinant Canine Carbonic Anhydrase IX/CA9 Protein (hFc Tag)_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kallio H, Tolvanen M, Jänis J, Pan PW, Laurila E, Kallioniemi A, Kilpinen S, Tuominen VJ, Isola J, Valjakka J, Pastorekova S, Pastorek J, Parkkila S. Characterization of non-specific cytotoxic cell receptor protein 1: a new member of the lectin-type subfamily of F-box proteins PLoS One. 2011;6(11):e27152._x000D_ 2: Swayampakula M, McDonald PC, Vallejo M, Coyaud E, Chafe SC, Westerback A, Venkateswaran G, Shankar J, Gao G, Laurent EMN, Lou Y, Bennewith KL, Supuran CT, Nabi IR, Raught B, Dedhar S. The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion Oncogene. 2017 Nov 9;36(45):6244-6261._x000D_ 3: Ramchandani D, Unruh D, Lewis CS, Bogdanov VY, Weber GF. Activation of carbonic anhydrase IX by alternatively spliced tissue factor under late-stage tumor conditions Lab Invest. 2016 Dec;96(12):1234-1245._x000D_ 4: Askoxylakis V, Garcia-Boy R, Rana S, Krämer S, Hebling U, Mier W, Altmann A, Markert A, Debus J, Haberkorn U. A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology PLoS One. 2010 Dec 31;5(12):e15962._x000D_ 5: McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy Clin Cancer Res. 2012 Jun 1;18(11):3100-11._x000D_ 6: He L, Zhao C, Li Y, Du G, Liu K, Cui D, Tang L, Wu X, Wen S, Chen H. Antiangiogenic effects of recombinant human endostatin in lung cancers Mol Med Rep. 2018 Jan;17(1):79-86._x000D_ 7: Zat'ovicová M, Tarábková K, Svastová E, Gibadulinová A, Mucha V, Jakubícková L, Biesová Z, Rafajová M, Ortova Gut M, Parkkila S, Parkkila AK, Waheed A, Sly WS, Horak I, Pastorek J, Pastoreková S. Monoclonal antibodies generated in carbonic anhydrase IX-deficient mice recognize different domains of tumour-associated hypoxia-induced carbonic anhydrase IX J Immunol Methods. 2003 Nov;282(1-2):117-34._x000D_ 8: Gallagher FA, Sladen H, Kettunen MI, Serrao EM, Rodrigues TB, Wright A, Gill AB, McGuire S, Booth TC, Boren J, McIntyre A, Miller JL, Lee SH, Honess D, Day SE, Hu DE, Howat WJ, Harris AL, Brindle KM. Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors Cancer Res. 2015 Oct 1;75(19):4109-18._x000D_ 9: Knudsen ES, Balaji U, Freinkman E, McCue P, Witkiewicz AK. Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential Oncotarget. 2016 Nov 29;7(48):78396-78411._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27020103">10: Jiang Y, Verbiest T, Devery AM, Bokobza SM, Weber AM, Leszczynska KB, Hammond EM, Ryan AJ. Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality Int J Radiat Oncol Biol Phys. 2016 Jun 1;95(2):772-81. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Canine Carbonic Anhydrase IX/CA9 Protein (hFc Tag) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>