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Anti-GD3 (Ecromeximab)-MC-Vc-PAB-SN38 ADC

This ADC product is comprised of an anti-GD3 monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38. The SN-38 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage.

Product Specifications

CAS Number

9007-83-4

Format

Solution

Shipping Conditions

Ice Packs

Storage Conditions

-20°C

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CHMP4B, NT (CHMP4B, C20orf178, SHAX1, Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, SNF7 homolog associated with Alix 1, SNF7-2, Vacuolar protein sorting-associated protein 32-2) (PE)
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