Anti-IL6 (Olokizumab)-SMCC-DM1 ADC
This ADC product is comprised of an anti-IL6 monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
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588781 50 µg
TNFRSF10C (CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID, TNF related TRAIL receptor, TNF related apoptosis-inducing ligand receptor 3, TRAIL receptor 3, antagonist decoy receptor for TRAIL/Apo-2L, decoy receptor 1, decoy without an intracellular domain, lymphocyte inhibitor of TRAIL, tumor necrosis factor receptor sup)
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