Anti-IL5 (Crenezumab)-SPDB-DM4 ADC
This ADC product is comprised of an anti-IL5 monoclonal antibody conjugated via a SPDB linker to DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-7069R-BF488 100 µL
GADD45G Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Sign In for Pricing
View Details 
RC215398L4V 200 µL
Dystrobrevin alpha (DTNA) (NM_001391) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
VAng-Lsx5817-1mgEcoli 1 mg (E. coli)
Recombinant Campylobacter Concisus hisC Protein (aa 1-365)
Sign In for Pricing
View Details