Anti-IL17A (Secukinumab)-SPDB-DM4 ADC
This ADC product is comprised of an anti-IL17A monoclonal antibody conjugated via a SPDB linker to DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15330697 1 Vial
Lentiviral human AAK1 shRNA (UAS) - Lentiviral human AAK1 shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details T9154-05G-HRP 100 µL
Tubulin, beta (Beta Tubulin, Tubulin beta Polypeptide, Tubulin beta-2 Chain, DAQB-47P19.9-001, dJ40E16.7, M40, MGC117247, MGC16435, OK/SW-cl.56, TUBB, TUBB Protein, TUBB 1, TUBB1, TUBB 2, TUBB2, TUBB 5, TUBB5, XXbac-BCX111D4.2-001) (HRP) discontinued
Sign In for Pricing
View Details 
LV657124 1.0 µg DNA
SPINK13 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
Sign In for Pricing
View Details 