Anti-IL17A (Secukinumab)-SPDB-DM4 ADC
This ADC product is comprised of an anti-IL17A monoclonal antibody conjugated via a SPDB linker to DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
123359-APC 100 µL
ANXA3 (Annexin A3, Annexin-3, Annexin III, Lipocortin III, Placental Anticoagulant Protein III, PAP-III, 35-alpha Calcimedin, Inositol 1,2-cyclic Phosphate 2-phosphohydrolase, ANX3) (APC)
Sign In for Pricing
View Details 
MBS7155622 Inquire
Rabbit anti-Drosophila melanogaster (Fruit fly) ph-p Polyclonal Antibody
Sign In for Pricing
View Details