Anti-ICAM1 (Enlimomab)-MC-MMAF ADC
This ADC product is comprised of an anti-ICAM1 Fab' fragment conjugated via a MC linker to MMAF. The MMAF is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAF binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
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135465 100 µg
XRCC6 (X-ray Repair Cross-complementing Protein 6, 5'-deoxyribose-5-phosphate Lyase Ku70, 5'-dRP Lyase Ku70, 70kD Subunit of Ku Antigen, ATP-dependent DNA Helicase 2 Subunit 1, ATP-dependent DNA Helicase II 70kD Subunit, CTC box-binding Factor 75kD Subunit, CTC75, CTCBF, DNA Repair Protein XRCC6, Lupus Ku Autoantigen Protein p70, Ku70, Thyroid-lupus Autoantigen, TLAA, X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 6, G22P1)
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