Anti-ERBB3 (Patritumab)-SMCC-DM1 ADC
This ADC product is comprised of an anti-ERBB3 monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
550-50S1 100 Units/Case
Filcons (disposable cell strainer cup type, 100 units) range between 10 and 500 um STERILE
Sign In for Pricing
View Details