Anti-ERBB2 (Margetuximab)-MC-Vc-PAB-SN38 ADC
This ADC product is comprised of an anti-ERBB2 monoclonal antibody conjugated via a MC-Vc-PAB linker to SN38. The SN-38 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
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MBS6299354-02 5x 0.2 mL
FKBP6, CT (FKBP6, FKBP36, Peptidyl-prolyl cis-trans isomerase FKBP6, 36kD FK506-binding protein, FK506-binding protein 6, Immunophilin FKBP36, Rotamase) (Biotin)
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