Anti-ERBB2 (Margetuximab)-SMCC-DM1 ADC
This ADC product is comprised of an anti-ERBB2 monoclonal antibody conjugated via a SMCC linker to DM1. The DM1 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4945806 1.0 µg DNA
Zfp191 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
NBP3-13788-100ug 100 µg
Mouse Monoclonal SURF5 Antibody (PCRP-MED22-2A7)
Sign In for Pricing
View Details MBS2501848-01 24 Tests
Human PCNA (Proliferating Cell Nuclear Antigen) ELISA Kit
Sign In for Pricing
View Details MBS2501848-02 48 Tests
Human PCNA (Proliferating Cell Nuclear Antigen) ELISA Kit
Sign In for Pricing
View Details