Anti-CTLA4 (Ticilimumab)-SPDB-DM4 ADC
This ADC product is comprised of an anti-CTLA4 monoclonal antibody conjugated via a SPDB linker to DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM1 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
172092-AF-HRP 100 µL
Estrogen Receptor (Estrogen Receptor alpha delta 4*5,6,7*/654 Isoform, Estrogen Receptor alpha delta 4 +49 Isoform, Nuclear receptor subfamily 3 group A member 1) (HRP)
Ask
View Details 
E7349 96 Tests
Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Mouse ELISA Kit
Ask
View Details