Anti-EDNBR (clone 5E9)-VC-MMAE ADC
This ADC product is comprised of an anti-EDNRB monoclonal antibody (clone 5E9) conjugated via a VC linker to MMAE. The MMAE is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.
Product Specifications
CAS Number
9007-83-4
Format
Solution
Shipping Conditions
Ice Packs
Storage Conditions
-20°C
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