Anti-CD70 (clone 1F6)-VC-AFP ADC

This ADC product is comprised of an anti-CD70 monoclonal antibody (clone 1F6) conjugated via a VC linker to AFP. The AFP is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, AFP binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.