Human ASF1A Protein

<strong>Human ASF1A Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011789_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> ASF1 anti-silencing function 1 homolog A Anti silencing function 1A protein, hAsf1a protein, HSPC146 protein, , ASF1 anti-silencing function 1 homolog A protein, ASFA-1, hCIA protein, CGI-98 protein, ASFA 1 protein, CIA protein, ASF1A, ASFA-1 protein, CGI_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Li F, Huang Q, Luster TA, Hu H, Zhang H, Ng WL, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling CM, Bagdatlioglu E, Almonte C, Labbe K, Silver H, Rabin AR, Jani K, Tsirigos A, Papagiannakopoulos T, Hammerman PS, Velcheti V, Freeman GJ, Qi J, Miller G, Wong KK. In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma Cancer Discov. 2020 Feb;10(2):270-287._x000D_ 2: Cheng Q, Wang L. LncRNA XIST serves as a ceRNA to regulate the expression of ASF1A, BRWD1M, and PFKFB2 in kidney transplant acute kidney injury via sponging hsa-miR-212-3p and hsa-miR-122-5p Cell Cycle. 2020 Feb;19(3):290-299._x000D_ 3: Wu ZH, Yang DL, Wang L, Liu J. Epigenetic and Immune-Cell Infiltration Changes in the Tumor Microenvironment in Hepatocellular Carcinoma Front Immunol. 2021 Dec 2;12:793343._x000D_ 4: Rai TS, Puri A, McBryan T, Hoffman J, Tang Y, Pchelintsev NA, van Tuyn J, Marmorstein R, Schultz DC, Adams PD. Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex Mol Cell Biol. 2011 Oct;31(19):4107-18._x000D_ 5: Tang Y, Poustovoitov MV, Zhao K, Garfinkel M, Canutescu A, Dunbrack R, Adams PD, Marmorstein R. Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly Nat Struct Mol Biol. 2006 Oct;13(10):921-9._x000D_ 6: Wu Y, Li X, Yu J, Björkholm M, Xu D. ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells Cell Death Dis. 2019 Jan 28;10(2):76._x000D_ 7: Yoon J, Kim SJ, An S, Cho S, Leitner A, Jung T, Aebersold R, Hebert H, Cho US, Song JJ. Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding J Mol Biol. 2018 Mar 16;430(6):822-841._x000D_ 8: Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, Zhang Q, Yu N, Ding X, Yang F, Tian S, Zhang K, Sun T, Yang J, Yao Z, Wu S, Shi L. USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization Nat Commun. 2018 Mar 29;9(1):1285._x000D_ 9: Passtoors WM, Boer JM, Goeman JJ, Akker EB, Deelen J, Zwaan BJ, Scarborough A, Breggen Rv, Vossen RH, Houwing-Duistermaat JJ, Ommen GJ, Westendorp RG, van Heemst D, de Craen AJ, White AJ, Gunn DA, Beekman M, Slagboom PE. Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R PLoS One. 2012;7(1):e27759._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31286799">10: Qiu F, Wang Y, Chu X, Wang J. ASF1A regulates H4(Y72) phosphorylation and promotes autophagy in colon cancer cells via a kinase activity Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):2754-2763. </a>_x000D_ _x000D_ <strong>Products Related to Human ASF1A Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>