anti-HIgG(Fc)Fab-C-PNU ADC

This ADC product is comprised of a Fab fragment of an anti-human IgG Fc specific polyclonal antibody conjugated via a cleavable linker to PNU-159682. The antibody poRoom Temperatureion is a Fab fragment of a secondary antibody and the drug poRoom Temperatureion, PNU-159682, is a cytotoxic small molecule which binds to DNA, causes DNA damage. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates.