Doxazosin (mesylate) (Standard)
Doxazosin (mesylate) (Standard) is the analytical standard of Doxazosin (mesylate) . This product is intended for research and analytical applications. Doxazosin mesylate (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.
Product Specifications
CAS Number
77883-43-3
Product Name Alternative
UK 33274 (mesylate) (Standard)
UNSPSC
12352005
Target
Adrenergic Receptor; Autophagy; Mitophagy; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/doxazosin-mesylate-standard.html
Smiles
O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OC5=CC=CC=C5OC4.CS(=O)(O)=O
Molecular Formula
C24H29N5O8S
Molecular Weight
547.58
References & Citations
[1]Sun, J.A., et al., Stereoselective binding of doxazosin enantiomers to plasma proteins from rats, dogs and humans in vitro. Acta Pharmacol Sin, 2013. 34 (12) : p. 1568-74.|[2]D'Eletto, R.D. and N.B. Javitt, Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol, 1989. 13 Suppl 2: p. S1-4; discussion S4.|[3]Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116 (6 Pt 2) : p. 1785-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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