TC-O 9311
TC-O 9311 is a potent orphan G protein-coupled receptor 139 (GPR139) agonist with an EC50 of 39 nM[1].
Product Specifications
CAS Number
[444932-31-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GPR139
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tc-o-9311.html
Purity
99.83
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NNC(NC1=C2C=CC=CC2=CC=C1)=O)C3=CC(OC)=CC(OC)=C3
Molecular Formula
C20H19N3O4
Molecular Weight
365.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Shi F, et al. Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139. ACS Med Chem Lett. 2011 Feb 28;2 (4) :303-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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