Ilicicolin F
Ilicicolin F is a fungal metabolite that has been found in Fusarium and has diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo (IC50s=0.43 and 0.37 μM, respectively) but not the E. coli ubiquinol oxidase cytochrome bd (IC50=85 μM) .2 Ilicicolin F is active against the fungi A. fumigatus and C. albicans (MICs=1.66-3.33 and 6.66-13.33 μg/mL, respectively) . It is cytotoxic to HeLa cells with an EC50 value of 0.003 μg/mL.
Product Specifications
CAS Number
22738-98-3
Product Name Alternative
LL-Z 1272ζ
UNSPSC
12352005
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ilicicolin-f.html
Smiles
O=CC1=C(C)C(Cl)=C(O)C(C/C=C(C)/C=C/[C@@]2(C)[C@H](C)[C@@H](OC(C)=O)CC([C@@H]2C)=O)=C1O
Molecular Formula
C25H31ClO6
Molecular Weight
462.96
References & Citations
[1]Ellestad, et al. Some new terpenoid metabolites from an unidentified fusarium species. Tetrahedron 25 (6), 1323-1334 (1969) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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