A1B11
Product Specifications
UNSPSC Description
A1B11 is a selective SIRT inhibitor (SIRT2:IC50=5.3 μM) that can be used in the study of neurodegenerative diseases[1].
Target Antigen
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/a1b11.html
Smiles
O=C(C1=CC=CC=C1NC2=CC=CC(C3=CN(N=N3)CCC4CCCC4)=C2)N
Molecular Weight
375.47
References & Citations
[1]Tatum P R, et al. Identification of novel SIRT2-selective inhibitors using a click chemistry approach[J]. Bioorganic & medicinal chemistry letters, 2014, 24(8): 1871-1874.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119889/A1B11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119889/
Clinical Information
No Development Reported
CAS Number
1602731-56-5
Curated Selection
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