A1B11
A1B11 is a selective SIRT inhibitor (SIRT2:IC50=5.3 μM) that can be used in the study of neurodegenerative diseases[1].
Product Specifications
CAS Number
[1602731-56-5]
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/a1b11.html
Smiles
O=C(C1=CC=CC=C1NC2=CC=CC(C3=CN(N=N3)CCC4CCCC4)=C2)N
Molecular Formula
C22H25N5O
Molecular Weight
375.47
References & Citations
[1]Tatum P R, et al. Identification of novel SIRT2-selective inhibitors using a click chemistry approach[J]. Bioorganic & medicinal chemistry letters, 2014, 24 (8) : 1871-1874.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT2
Curated Selection
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