AB-423
AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells.
Product Specifications
CAS Number
[1572510-80-5]
Product Name Alternative
(R) -DVR-23
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/AB-423.html
Purity
99.31
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=CC=C(F)C(F)=C1)C2=CC(S(=O)(N[C@H](C)CC)=O)=CC=C2F
Molecular Formula
C17H17F3N2O3S
Molecular Weight
386.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Mani N, et al. Preclinical profile of AB-423, an inhibitor of Hepatitis B virus pgRNA encapsidation. Antimicrob Agents Chemother. 2018 Mar 19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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