(S, R, S) -AHPC-Ala-CO-cyclohexene-Bpin

(S, R, S) -AHPC-Ala-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S, R, S) -AHPC-Ala-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-23 (HY-163876) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-ala-co-cyclohexene-bpin.html

Smiles

O=C(N1[C@@H](C[C@H](C1)OC([C@@H](N)C)=O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(C4CC=C(B5OC(C)(C)C(C)(C)O5)CC4)=O

Molecular Formula

C38H54BN5O7S

Molecular Weight

735.74

References & Citations

[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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