Lariciresinol
Lariciresinol is an orally active ingredient. Lariciresinol can be isolated from Arabidopsis thaliana. Lariciresinol inhibits α-glucosidase activity (IC50 of 6.97 μM; Ki of 0.046 μM) . Lariciresinol dereases Bcl-2, upregulates Bax and induces Apoptosis. Lariciresinol regulates TGF-β and NF-κB pathways. Lariciresinol has antitumor activity against liver cancer, gastric cancer, and breast cancer. Lariciresinol shows antifungal activity and anti-diabetic activity[1][2][3][4][5][6][7][8].
Product Specifications
CAS Number
27003-73-2
UNSPSC
12352005
Hazard Statement
H400
Target
Apoptosis; Bcl-2 Family; Fungal; Glycosidase; NF-κB; TGF-β Receptor
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease; NF-κB; TGF-beta/Smad
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lariciresinol.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : 25 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@](C(C=C2)=CC(OC)=C2O)([H])OC[C@@H]1CC(C=C3)=CC(OC)=C3O
Molecular Formula
C20H24O6
Molecular Weight
360.40
Precautions
H400
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Glucosidase
Frequently Asked Questions
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