CSF-1-R Recombinant Rabbit Monoclonal Antibody [PSH06-70]
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Csf1r, Csfmr, Fms
Swiss Prot
P09581 Mouse
Cellular Locus
Cell membrane
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant protein within mouse CSF-1-R aa 1-536.
Isotype
IgG
Clone
PSH06-70
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
RAW264.7 cell lysate, J774A.1 cell lysate, RAW264.7.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 109 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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