Human ACE2 Conjugated to Phosphatase Alkaline

<strong>Human ACE2 Conjugated to Phosphatase Alkaline</strong>_x000D_ <strong>Catalog number:</strong> B2010704_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> na_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> versatile molecular tool in the research and development of assays involving the human recptor ACE2_x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> ACE2 Alkaline Phosphatase, Alkaline Phosphatase conjugated to ACE2. ACE2-AP conjugate, ACE2 [AP], ACE2 ALP-Conjugated_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Senapati S, Banerjee P, Bhagavatula S, Kushwaha PP, Kumar S. Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19 J Genet. 2021;100(1):12._x000D_ 2: Li MY, Li L, Zhang Y, Wang XS. Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues Infect Dis Poverty. 2020 Apr 28;9(1):45._x000D_ 3: Zou X, Chen K, Zou J, Han P, Hao J, Han Z. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection Front Med. 2020 Apr;14(2):185-192._x000D_ 4: Beyerstedt S, Casaro EB, Rangel ÉB. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection Eur J Clin Microbiol Infect Dis. 2021 May;40(5):905-919._x000D_ 5: Hussain M, Jabeen N, Raza F, Shabbir S, Baig AA, Amanullah A, Aziz B. Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein J Med Virol. 2020 Sep;92(9):1580-1586._x000D_ 6: Zhang H, Rostami MR, Leopold PL, Mezey JG, O'Beirne SL, Strulovici-Barel Y, Crystal RG. Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium Am J Respir Crit Care Med. 2020 Jul 15;202(2):219-229._x000D_ 7: Ashraf UM, Abokor AA, Edwards JM, Waigi EW, Royfman RS, Hasan SA, Smedlund KB, Hardy AMG, Chakravarti R, Koch LG. SARS-CoV-2, ACE2 expression, and systemic organ invasion Physiol Genomics. 2021 Feb 1;53(2):51-60._x000D_ 8: Devaux CA, Rolain JM, Raoult D. ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome J Microbiol Immunol Infect. 2020 Jun;53(3):425-435._x000D_ 9: Chakraborty S. Evolutionary and structural analysis elucidates mutations on SARS-CoV2 spike protein with altered human ACE2 binding affinity Biochem Biophys Res Commun. 2021 Jan 1;534:374-380._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32623480">10: Mercurio I, Tragni V, Busto F, De Grassi A, Pierri CL. Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies Cell Mol Life Sci. 2021 Feb;78(4):1501-1522. </a>_x000D_ _x000D_ <strong>Products Related to Human ACE2 Conjugated to Phosphatase Alkaline</strong><a href="https://moleculardepot.com/product-category/Conjugates/">: Conjugates</a>