11 ß-HSD1 HDR Plasmid

<strong>11 ß-HSD1 HDR Plasmid</strong>_x000D_ <strong>Catalog number:</strong> B2015202_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ¬µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2 - 8 ¬∞C_x000D_ <strong>Keywords:</strong> 11 ß-HSD1 HDR Plasmid_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Scott JS, Goldberg FW, Turnbull AV. Medicinal chemistry of inhibitors of 11 ß-hydroxysteroid dehydrogenase type 1 (11 ß-HSD1) J Med Chem. 2014 Jun 12;57(11):4466-86._x000D_ 2: Singh R, Bhardwaj VK, Das P, Purohit R. Identification of 11 ß-HSD1 inhibitors through enhanced sampling methods Chem Commun (Camb). 2022 Apr 19;58(32):5005-5008._x000D_ 3: Hale C, Wang M. Development of 11beta-HSD1 inhibitors for the treatment of type 2 diabetes Mini Rev Med Chem. 2008 Jun;8(7):702-10._x000D_ 4: Li X, Qiu W, Deng L, Lin J, Huang W, Xu Y, Zhang M, Jones NC, Lin R, Xu H, Lin L, Li P, Wang X. 11 ß-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice J Transl Med. 2022 Sep 5;20(1):406._x000D_ 5: Fang CH, Li YP, Li Y, Yue JM, Bao J, Yu JH. Triterpenoids with multi-skeletons as 11 ß -HSD1 inhibitors from Euphorbia sikkimensis Phytochemistry. 2023 Jul;211:113684._x000D_ 6: Chen Y, Li J, Zhang M, Yang W, Qin W, Zheng Q, Chu Y, Wu Y, Wu D, Yuan X. 11 ß-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway Nutrients. 2022 Jun 6;14(11):2358._x000D_ 7: Odermatt A, Atanasov AG, Balazs Z, Schweizer RA, Nashev LG, Schuster D, Langer T. Why is 11beta-hydroxysteroid dehydrogenase type 1 facing the endoplasmic reticulum lumen? Physiological relevance of the membrane topology of 11beta-HSD1 Mol Cell Endocrinol. 2006 Mar 27;248(1-2):15-23._x000D_ 8: Westgate CSJ, Markey K, Mitchell JL, Yiangou A, Singhal R, Stewart P, Tomlinson JW, Lavery GG, Mollan SP, Sinclair AJ. Increased systemic and adipose 11 ß-HSD1 activity in idiopathic intracranial hypertension Eur J Endocrinol. 2022 Jul 4;187(2):323-333._x000D_ 9: Harno E, White A. Will treating diabetes with 11 ß-HSD1 inhibitors affect the HPA axis? Trends Endocrinol Metab. 2010 Oct;21(10):619-27._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23612224">10: Gathercole LL, Lavery GG, Morgan SA, Cooper MS, Sinclair AJ, Tomlinson JW, Stewart PM. 11 ß-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects Endocr Rev. 2013 Aug;34(4):525-55. </a>_x000D_ _x000D_ <strong>Products Related to 11 ß-HSD1 HDR Plasmid can be found at</strong> <a href="https://moleculardepot.com/product-category/DNA/"> DNA</a>