Tosufloxacin (tosylate hydrate)

Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria[1][2].

Product Specifications

CAS Number

[1400591-39-0]

Product Name Alternative

A-61827 (tosylate hydrate) ; T-3262

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Tosufloxacin-tosylate-hydrate.html

Purity

99.95

Solubility

DMSO : 12.5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

CC1=CC=C(S(=O)(O)=O)C=C1.O=C(C2=CN(C3=CC=C(F)C=C3F)C4=C(C=C(F)C(N5CC(N)CC5)=N4)C2=O)O.O

Molecular Formula

C26H25F3N4O7S

Molecular Weight

594.56

Precautions

H302, H315, H319, H335

References & Citations

[1]Chu DT, et al. Synthesis and biological properties of A-71497: a prodrug of tosufloxacin. Drugs Exp Clin Res. 1990;16 (9) :435-43.|[2]Fujimaki K, et al. In vitro and in vivo antibacterial activities of T-3262, a new fluoroquinolone. Antimicrob Agents Chemother. 1988 Jun;32 (6) :827-33.