2-Amino-2- (p-tolyl) acetic acid
Selected Variant
HY-W006187-01
Size: 1 g
2-Amino-2- (p-tolyl) acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) [1][2].
Product Specifications
CAS Number
13227-01-5
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Glutaminase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-amino-2-p-tolyl-acetic-acid.html
Purity
97.0
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(O)C(N)C1=CC=C(C)C=C1
Molecular Formula
C9H11NO2
Molecular Weight
165.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139 (41) :14396–14398.|[2]Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Price
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