JNK-IN-11

JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].

Product Specifications

CAS Number

[676594-38-0]

UNSPSC

12352005

Target

JNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/jnk-in-11.html

Purity

98.01

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(NC(CC2=CC=CS2)=O)C=CS1)OC

Molecular Formula

C12H11NO3S2

Molecular Weight

281.35

References & Citations

[1]Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20 (24) :7303-7.