(2R,2R) -PF-07258669
(2R,2R) -PF-07258669 is a MC4R (melanocortin 4 receptor) antagonist. (2R,2R) -PF-07258669 can be used in the study of regulating appetite and energy expenditure[1].
Product Specifications
CAS Number
2755890-68-5
UNSPSC
12352005
Target
Melanocortin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2r-2r-pf-07258669.html
Purity
99.64
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(N=C(N1)C(CC[C@@]21CCN(C([C@H](C)C3=C(C=NC(OC)=C3)F)=O)C2)=C4)=C4C5=NC=CC=N5
Molecular Formula
C25H27FN6O2
Molecular Weight
462.52
References & Citations
[1]Cao Q, et al. Modular, automated synthesis of spirocyclic tetrahydronaphthyridines from primary alkylamines[J]. Communications Chemistry, 2023, 6 (1) : 215.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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