CART (55-102) (human) (TFA)

CART (55-102) (human) TFA is a human satiety factor with potent appetite-suppressing activity. CART (55-102) (human) TFA is closely associated with leptin and neuropeptide Y[1][2].

Product Specifications

UNSPSC

12352209

Target

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cart-55-102-human-tfa.html

Solubility

10 mM in DMSO

Smiles

OC(C(F)(F)F)=O.O=C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](C(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCSC)C(N[C@@H](CSSC[C@@H](C(N5[C@@H](CCC5)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@H](O)C)C(N[C@H]6CO)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@H]9CCCCN)=O)=O)=O)=O)=O)=O)NC6=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(C)C)C(O)=O)=O)NC9=O)C(N[C@H]7CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N

Molecular Formula

C227H366F3N65O67S7

Molecular Weight

5359.18

References & Citations

[1]K Matsumura, et al. Central Human Cocaine- And Amphetamine-Regulated Transcript Peptide 55-102 Increases Arterial Pressure in Conscious Rabbits. Hypertension. 2001 Nov;38 (5) :1096-100.|[2]H Volkoff, et al. Effects of CART Peptides on Food Consumption, Feeding and Associated Behaviors in the Goldfish, Carassius Auratus: Actions on Neuropeptide Y- And Orexin A-induced Feeding. Brain Res. 2000 Dec 22;887 (1) :125-33.