STAT3/AKT-IN-1
STAT3/AKT-IN-1 is a dual inhibitor for the signal transducer and activator of transcription 3 (STAT3) and protein kinase B (AKT) signalling pathway, exhibits antitumor activity against gastric cancer and induces cell apoptosis in SGC-7901 cells[1].
Product Specifications
UNSPSC
12352005
Target
Akt; Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-akt-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1/C(CC/C1=C\C=C\C2=CC=CC=C2OC)=C/C3=CC=C(O)C(OC)=C3
Molecular Formula
C23H22O4
Molecular Weight
362.42
References & Citations
[1]Gan X, et al., Design, synthesis, and evaluation of cyclic C7-bridged monocarbonyl curcumin analogs containing an o-methoxy phenyl group as potential agents against gastric cancer. J Enzyme Inhib Med Chem. 2024 Dec;39 (1) :2314233.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3
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