D-Glucaric acid (potassium)

D-Glucaric acid potassium (Potassium D-glucarate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid potassium is present in a variety of fruits and vegetables. D-Glucaric acid potassium has cholesterol-lowering and anti-tumor activities. D-Glucaric acid potassium can inhibit tumor cell proliferation and inflammation, and induce apoptosis[1][2].

Product Specifications

CAS Number

[576-42-1]

Product Name Alternative

Potassium D-glucarate

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Apoptosis; Endogenous Metabolite

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/d-glucaric-acid-monopotassium-salt.html

Purity

98.0

Solubility

H2O : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]([C@H]([C@@H]([C@@H](C([O-])=O)O)O)O)C(O)=O.[K+]

Molecular Formula

C6H9KO8

Molecular Weight

248.23

Precautions

H315, H319, H335

References & Citations

[1]Walaszek Z, et al. D-glucaric acid content of various fruits and vegetables and cholesterol-lowering effects of dietary D-glucarate in the rat. Nutrition Research, 1996, 16 (4) : 673-681.|[2]Zółtaszek R, et al. Biologiczna rola kwasu D-glukarowego i jego pochodnych; potencjalne zastosowanie w medycynie [The biological role of D-glucaric acid and its derivatives: potential use in medicine]. Postepy Hig Med Dosw (Online) . 2008 Sep 5;62:451-62.