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Corydalmine

Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi[1]. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity[2]. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway[3].

Product Specifications

CAS Number

[30413-84-4]

Product Name Alternative

L-Corydalmine; TLZ-16

UNSPSC

12352005

Hazard Statement

H315-H319

Target

CXCR; Fungal

Type

Natural Products

Related Pathways

Anti-infection; GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/corydalmine.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@]3([H])C2)=C1OC

Molecular Formula

C20H23NO4

Molecular Weight

341.40

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

Corydalis Chaerophylla

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

CXCR2

Available Sizes

Curated Selection

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