ODN 1585 (sodium)
Product Specifications
UNSPSC Description
ODN 1585 is a potent inducer of IFN and TNFα production. ODN 1585 is a potent stimulator of NK (natural killer) function. ODN 1585 increases CD8+ T-cell function, including the CD8+ T cell-mediated production of IFN-γ. ODN 1585 induces regression of established melanomas in mice. ODN 1585 can confer complete protection against malaria in mice. ODN 1585 sodium can be used for acute myelogenous leukemia (AML) and malaria research. ODN 1585 can be used as a vaccine adjuvant[1][2][3].
Target Antigen
IFNAR; TNF Receptor
Type
Oligonucleotides
Related Pathways
Apoptosis;Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/odn-1585-sodium.html
Solubility
10 mM in H2O
Smiles
[DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G), sodium salt]
Molecular Weight
6889.80
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150725C/ODN-1585-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150725C/ODN-1585-sodium-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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