Ganoderic acid R
Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1) [1].
Product Specifications
CAS Number
103963-39-9
UNSPSC
12352211
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ganoderic-acid-r.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@@H](CC2)OC(C)=O)C
Molecular Formula
C34H50O6
Molecular Weight
554.76
References & Citations
[1]Ouyang J J, et al. Ganoderic Acid Restores the Sensitivity of Multidrug Resistance Cancer Cells to Doxorubicin. Advanced Materials Research, 2014, 834-836:573-576.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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