Selenocystine
Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs) . Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].
Product Specifications
CAS Number
2897-21-4
UNSPSC
12352209
Hazard Statement
H301+H331, H373, H410
Target
Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/selenocystine.html
Purity
99.0
Solubility
1 M HCl : 100 mg/mL (adjust pH to 1 with H2O)
Smiles
NC(C[Se][Se]CC(C(O)=O)N)C(O)=O
Molecular Formula
C6H12N2O4Se2
Molecular Weight
334.09
Precautions
H301+H331, H373, H410
References & Citations
[1]Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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