Selenocystine

Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs) . Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].

Product Specifications

CAS Number

[2897-21-4]

UNSPSC

12352209

Hazard Statement

H301+H331, H373, H410

Target

Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/selenocystine.html

Purity

99.0

Solubility

1 M HCl : 100 mg/mL (adjust pH to 1 with H2O)

Smiles

NC(C[Se][Se]CC(C(O)=O)N)C(O)=O

Molecular Formula

C6H12N2O4Se2

Molecular Weight

334.09

Precautions

H301+H331, H373, H410

References & Citations

[1]Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046.