Sapintoxin D

Sapintoxin D is a fluorescent phorbol ester that can be used to study the activation of protein kinase C (PKC) . Sapintoxin D is a calcium-dependent PKC activator[1].

Product Specifications

CAS Number

[80998-07-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

PKC

Type

Natural Products

Related Pathways

Epigenetics; TGF-beta/Smad

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sapintoxin-d.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O[C@H]([C@H]1C)[C@]2(OC(C)=O)[C@@]([C@@](C=C(CO)C[C@]34O)([H])[C@@]1(O)[C@]4([H])C=C(C)C3=O)([H])C2(C)C)C5=CC=CC=C5NC

Molecular Formula

C30H37NO8

Molecular Weight

539.62

Precautions

H315, H319, H335

References & Citations

[1]Slater SJ, et al., Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities. J Biol Chem. 1996 Mar 1;271 (9) :4627-31.