Eluvixtamab
Eluvixtamab (AMG-330) is a bispecific T-cell engager. Eluvixtamab binds to CD33 and CD3 on T cells, thereby promoting T cell-mediated cytotoxicity against CD33+ cells. Eluvixtamab can be used in the research of tumors such as relapsed/refractory acute myeloid leukemia[1].
Product Specifications
CAS Number
[1679391-73-1]
Product Name Alternative
AMG-330
UNSPSC
12352203
Target
CD3; Transmembrane Glycoprotein
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/eluvixtamab.html
Purity
97.28
Smiles
[Eluvixtamab]
Molecular Weight
(54.34 kDa)
References & Citations
[1]Ravandi F, et al. Safety and tolerability of AMG 330 in adults with relapsed/refractory AML: a phase 1a dose-escalation study. Leuk Lymphoma. 2024 Sep;65 (9) :1281-1291.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Available Sizes
Curated Selection
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