TRKA Protein Active (440-end)

<strong>TRKA Protein Active (440-end)</strong>_x000D_ <strong>Catalog number:</strong> B2013823_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 66 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> DKFZp781l14186, MTC, NTRK1, TRK1, p140-TrKA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Reichardt LF. Neurotrophin-regulated signalling pathways Philos Trans R Soc Lond B Biol Sci. 2006 Sep 29;361(1473):1545-64._x000D_ 2: Minnone G, De Benedetti F, Bracci-Laudiero L. NGF and Its Receptors in the Regulation of Inflammatory Response Int J Mol Sci. 2017 May 11;18(5):1028._x000D_ 3: Amatu A, Sartore-Bianchi A, Siena S. NTRK gene fusions as novel targets of cancer therapy across multiple tumour types ESMO Open. 2016 Mar 18;1(2):e000023._x000D_ 4: Fahnestock M, Shekari A. ProNGF and Neurodegeneration in Alzheimer's Disease Front Neurosci. 2019 Feb 22;13:129._x000D_ 5: Zanin N, Blouin CM. [Endosomal control of intracellular signaling] Biol Aujourdhui. 2018;212(1-2):45-51._x000D_ 6: Hassiepen C, Soni A, Rudolf I, Boron V, Oeck S, Iliakis G, Schramm A. NTRK1/TrkA Activation Overrides the G(2)/M-Checkpoint upon Irradiation Cancers (Basel). 2021 Nov 30;13(23):6023._x000D_ 7: Tsuruda A, Suzuki S, Maekawa T, Oka S. Constitutively active Src facilitates NGF-induced phosphorylation of TrkA and causes enhancement of the MAPK signaling in SK-N-MC cells FEBS Lett. 2004 Feb 27;560(1-3):215-20._x000D_ 8: Lange AM, Lo HW. Inhibiting TRK Proteins in Clinical Cancer Therapy Cancers (Basel). 2018 Apr 4;10(4):105._x000D_ 9: Duan L, Hope JM, Guo S, Ong Q, Franois A, Kaplan L, Scherrer G, Cui B. Optical Activation of TrkA Signaling ACS Synth Biol. 2018 Jul 20;7(7):1685-1693._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37036720">10: Testa G, Mainardi M, Vannini E, Pancrazi L, Cattaneo A, Costa M. Disentangling the signaling complexity of nerve growth factor receptors by CRISPR/Cas9 FASEB J. 2022 Nov;36(11):e22498. </a>_x000D_ _x000D_ <strong>Products Related to TRKA Protein Active (440-end) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>